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Estimates of the annual volume of ill-gotten gains laundered through the UK vary enormously.
Management strategies for neutropenic patients in the ICU often rely on low-grade evidence derived from an extensive but sometimes contradictory medical literature partly ascribable to small single-center observational cohort studies, variability regarding centers experience and volume of critically ill cancer patients, and relatively old studies.
Australian and New Zealand Clinical Trials Registry ACTRN12610001012066. Resuscitation of intravascular volume of critically ill patients is essential for hemodynamic support [ 1- 3].
Although the above estimates of the potential numbers of critically ill patients were crude at best, both suggested that, during the influenza pandemic, healthcare workers (HCWs) in ICUs should be prepared to provide critical care support for an excessive volume of critically ill patients over the course of several months.
"Given these facts and the sheer volume of his ill-gotten gains -- over $73 million in city contracts -- Ferguson is deserving of a sentence at or near that of Kilpatrick," the attorneys concluded.
Although CVP has been utilized as a surrogate of intravascular volume in critically ill patients, recent studies have challenged the validity of elevated CVP (ECVP) in critical care settings [5 9].
In contrast, little evidence supports the use of lower tidal volume in critically ill patients without ALI/ARDS, partly because of a lack of randomized controlled trial evidence on the best ventilator strategies in these patients [ 8].
Is there evidence that blood conservation devices reduce the volume of blood taken from critically ill patients?
During the past 20 years, a number of trials have shown that the use of a blood conservation device can reduce the volume of blood taken from critically ill patients.
(2) It remains unknown that whether the side effects of bradycardia and hypotension of dexmedetomidine may affect cardiac output or stroke volume in critically ill patients. .
Taccone and colleagues [ 19] confirmed the hypothesis that, in critically ill patients, increased volume of distribution (Vd) of hydrophilic drugs affects the disposition of aminoglycosides and therefore a revisited amikacin loading dose of 25 mg/kg should be required to attain the target concentration and the optimized Cmax/MIC ratio.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com