Sentence examples for vivo presentation from inspiring English sources

The increased in vivo presentation by K3−MuHV-4 of p79 [16], an epitope presented largely by B cells [20], suggests that K3 might also be important for reactivation, but it has not been possible to analyze the effect of K3 disruption on reactivation titers.

We present a strategy to conjugate TGF-β1 into fibrin hydrogels to mimic the in vivo presentation of the growth factor in a 3D context.

Attempts to model in vivo presentation of TGN1412 have focused on endothelial cell co-cultures 4– 11 and more recently pre-culture of peripheral blood mononuclear cells (PBMC) at high density 12, with promising results.

Thus we believe the novelty lies in the linking of particle size to in vivo presentation kinetics/dynamics, the activation and differentiation of CD4 T cells and induction of protective antibody responses.

Although the solid phase assay does not replicate in vivo presentation of TGN1412, which is not fully understood, it does induce substantial cytokine release equivalent to that reported in trial volunteers.

In contrast, the TG muscles developed a constant increase in diastolic tension up to 3.7 ± 0.4 mN/mm compared to WT specimen with 2.5 ± 0.2 mN/mm (n = 11 vs. 10, RM-ANOVA P < 0.05), which we interpret as an ex vivo presentation of diastolic dysfunction.

In-vivo presentation assays using HspBP1 deficient transgenic mice confirmed the regulatory role of the CHIP-inhibitor in antigen presentation.

In conclusion, the results of this study extend previous studies suggesting that for optimal CD8 T cell adoptive therapy, it is more efficacious to reactivate memory T cells before infusion, rather than relying on in vivo antigen presentation.

We used a direct ex vivo antigen presentation assay to probe the capacity of flow cytometrically purified DC populations to drive amplification of CD4+ and CD8+ T cells following infection with influenza virus by different routes.

In vivo, GPIbα presentation is highly variable under different physiological and pathophysiological conditions.

We further showed that fast-acting drugs that reduce the parasite load in vivo reduce presentation and prevent ECM death.