In vivo models of arterial thrombosis and thrombolysis.
Winer BY, Ding Q, Gaska JM, Ploss A. In vivo models of hepatitis B and C virus infection.
Malagelada, C., Jin, Z. H., Jackson-Lewis, V., Przedborski, S. & Greene, L. A. Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease.
Both in in vitro and in vivo models of PD, it has been demonstrated that NCLX is an essential regulator of mitochondrial Ca2+ homeostasis17,18.
Compound 11 was active in in vivo models of stress urinary incontinence.
In vivo models of Inflammatory Bowel Diseases (IBD) elucidate important mechanisms of chronic inflammation.
S2-P activity has been evaluated in cellular and in vivo models of inflammation.
The lab uses an approach that includes in silico mathematical and computational modeling, in vitro characterization and novel platform development, and in vivo models of cancer.
Future studies would establish whether ACV could be used as a potential therapeutic, In vivo models of infection could be induced by infusing microbes systemically into mice followed by treatment with or without intraperitoneal ACV.
Patient-specific ex vivo models of human tumours that recapitulate the pathological characteristics and complex ecology of native tumours could help determine the most appropriate cancer treatment for individual patients.
These complex cell-to-cell interactions and corresponding sequence of events leading to degeneration are difficult to capture and recapitulate by ex vivo models of human disease, making development and testing of potential treatments a particularly challenging and expensive endeavor.
