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All infectious in vitro work was performed in the BSL4 laboratory of NML, PHAC.
All infectious in vitro work was performed in the high containment laboratory of NML/PHAC.
All infectious in vitro work was performed in the BSL4 laboratory at the NML, PHAC.
However, whilst in vitro work was promising, in vivo pharmacological blockade of AQP1 did not have a significant effect.
While this in vitro work was in progress, an article by Wang and co-workers was published (13) in which in vitro replication of the G[8,5-Me]T lesion by yeast DNA polymerase η was reported.
The in vitro work was carried out in THP-1 cells rather than alveolar macrophages, as these are difficult to obtain in large enough numbers to perform the necessary experiments.
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For the application of nanotechnology in medicine, 'in vitro' work is of paramount importance, especially regarding the assessment of possible toxicological consequences of the nanomaterials/NPs.
Additional field- and in vitro work is required to define the phenotypic consequences of CD36 deficiency alleles in health and disease.
In vitro works are generally not fully representative of a reliable physiological condition.
Additionally, it should be noted that our in vitro signaling work was performed in VSMCs harvested from rats as opposed to mice.
Data from comparative groups in the in vivo study and the in vitro drug combination work was compared using ANOVA (either two way or two way repeated measures, as appropriate) in the Graphpad Prism software package.
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