Sentence examples for vitro we have from inspiring English sources

In order to evaluate their transport in aqueous media in vitro, we have used and compared SEC, UV, ITC, and NMR techniques.

Consistent with the function of FXYD6 in endowing HCC cells survival advantage (Fig. 2) in vitro, we have also shown that blockade of FXYD6 activity by its functional antibody can significantly reduce the volume and weight of xenografted tumors originated from HCC cells in vivo (Fig. 5), suggesting that FXYD6 is an important mediator in tumor development.

In order to study whether the inconsistent results could be explained by different systems having different potential for DMHA to be formed and to induce genotoxicity in vitro, we have tested 2,6-xylidine in conventional Ames bacteria, and strains engineered to overexpress acetyltransferase, in the presence of different concentrations of induced rat liver and human liver S9.

In our attempts to reconstruct these events in vitro we have previously linked in tandem two copies of the C-terminal half barrel HisF-C of imidazole glycerol phosphate synthase from Thermotoga maritima and subsequently reconstituted in the fusion construct HisF-CC a salt bridge cluster present in wild-type HisF.

In vitro we have shown already that the presence of simple organic MLE compounds can enhance encephalitogenic T cell responses [12], [13].

During probing the template effect of DNA in WT SOD1 aggregation in vitro, we have found that the DNA-mediated enrichment of and the acidic pH-triggered hydrophobic alteration of the SOD1 protein are two key steps for aggregation [33].

To isolate clonal ESC-derived lineage-restricted cell lines with endothelial potential and the capacity for self-renewal in vitro, we had to use a combination of empirical and rational evidence-based methods to gradually circumvent the lack of definitive selectable markers.

As TNRC6B can complement silencing in S2 cells and a single point mutation in TNRC6B is sufficient to prevent binding to PABPC1 both in vivo and in vitro, we had the opportunity to test whether the TNRC6B PABPC1 interaction is relevant for silencing in a cellular context.

Using an established model of in vitro hypoxia, we have analyzed the expression of genes involved in bone matrix production and turnover.

The in vitro results we have obtained indicate that this strategy is very effective in eradicating both differentiated cancer cells and CICs in several types of malignant disease.

In summary, using an in vitro model, we have found that treatment with pravastatin results in a reduction of MMP-3 and MMP-9 mRNA expression and MMP enzyme activity.