Velocity and equilibrium sedimentation analysis of pulse-chased and labeled DNA using radioactive and density labels suggested that SV40 DNA synthesis in vitro was a continuation of normal ongoing DNA synthesis.
Primary hepatocytes are commonly used as liver surrogates in toxicology and tissue engineering fields, therefore, maintenance of functional hepatocytes in vitro is an important topic of investigation.
Functionally, however, the dominant phenotype observed in vitro is an inability to generate differentiated progeny, with self-renewal effectively uncompromised in culture.
PKC dephosphorylation enhanced the chemosensitivity to cisplatin of cancer cells in vitro is an example of such an approach.
22 Hypoxia, in vitro, is an important regulator of angiogenesis, migration, cell survival pathways and matrix degradation.
The inability of endometriotic epithelial cells to survive in vitro is an obstacle to gaining a better understanding of the biology of this disease.
The ability to continue growing in the apparent absence of nitrogen (albeit at reduced growth rate) in vitro is an interesting observation.
Elucidating the toxicological mechanisms that link specific chemical and physical characteristics of inhaled particles with biological responses in vivo and in vitro is an active area of research.
Vitro is a study in paradoxes.
