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By way of very brief explanation, a human brain organoid is a structure of cells created in vitro through the stimulation of human stem cells.
Borman, A. M., Michel, Y. M., Malnou, C. E. & Kean, K. M. Free poly(A) stimulates capped mRNA translation in vitro through the eIF4G-poly(A -binding protein interA -binding
Despite compelling data supporting a model for the assembly of endothelial tubes in vitro through the formation and fusion of vacuoles, conclusive evidence in vivo has been lacking, primarily because of difficulties associated with imaging the dynamics of subcellular endothelial vacuoles deep within living animals.
We highlight and discuss current issues associated with the development of mathematical models of biological systems and share our perspective towards a holistic 'closed loop' approach that will facilitate the control of the in vitro through the in silico.
An anti-autoinducer monoclonal antibody, AP4-24H11, was elicited against a rationally designed hapten, and efficiently inhibited QS in vitro through the sequestration of the autoinducing peptide (AIP -4 produced by S. AIP -4 RN4850.
Recent research has also indicated promising results through experiments performed in vitro through the use of human corneal epithelial [51] cells.
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Ek et al (2007a) and Takenaka et al (2005) later showed that PEDF restricted osteosarcoma growth in vitro through both the induction of apoptosis and the inhibition of cell cycling.
These results demonstrated that cortactin and Tir interact directly in vitro, through both the N-terminal region and the SH3 domain of cortactin, and this interaction seems to occur independently of cortactin phosphorylation.
Hence, our data show that BBR may inhibit the Hh-dependent medulloblastoma cells growth in vitro through inhibiting the Hh pathway activity.
The combination of TMZ with cisplatin is synergistic in in-vitro through the downregulation of the activity of the DNA repair enzyme o alkylguanine-DNA-alkyltransferase, which mediates the resistance to alkylguanine-DNA-alkyltransferase
These findings suggest that glucosamine can inhibit primary tumor formation in vivo as well as cell proliferation in vitro through restraining the IGF-1R/Akt signaling by glucosamine-induced ER-stress.
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