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Antibiotic therapy was considered appropriate if the first-line treatment included at least one antibiotic active in vitro on the isolated microorganism.
Initial adequate antibiotic therapy was defined as one or more antibiotics active in vitro on the identified microorganisms or, in non-documented CAP, as treatment according to current guidelines [ 5], started at ICU admission and not requiring a change (secondary adjustment of antibiotic therapy) upon re-evaluation 48 hours later.
A series of novel indole-imidazole derivatives have been prepared and evaluated in vitro on the aromatase inhibitory activities.
Possible antitumor properties resulting thereof were evaluated in vitro on the human MCF-7 breast cancer cell line.
The ability of 14S24 to repair the disturbed skin barrier was evaluated in vitro on the porcine skin.
The low cytotoxicity of GP facilitated cell proliferation and extracellular matrix (ECM) secretion in vitro on the crosslinked scaffolds over 7 days.
NIH 3T3 fibroblasts proliferated in vitro on the PCL and PCL/SF scaffolds for 7 days, but there was no statistical difference between the groups.
NSCs that were cultured in vitro on the scaffold differentiated into neurons and astrocytes, as indicated by their expression of βIII-tubulin and glial fibrillary acidic protein (GFAP).
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In addition to evaluating the efficacy of AMF exposures in vitro on biofilm, the feasibility of translating this treatment strategy to a human-sized implant was investigated through numerical simulations and phantom studies.
Human umbilical vein endothelial cells adhesion tests were performed in vitro on all the samples.
In vitro studies on the action of CS-0455, a new anti-diabetic agent.
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