Sentence examples for vitro neural stem from inspiring English sources
This brief review focuses on engineered peptide and protein materials suitable for use as in vitro neural stem cell niche mimics and in vivo central nervous system repair.
Neurite outgrowth is a metric widely used to assess the success of in vitro neural stem cell differentiation or neuron reprogramming protocols and to evaluate high-content screening assays for neural regenerative drug discovery.
As the structure of PLLA scaffold was intended for neural tissue engineering, its suitability was evaluated in vitro using neural stem cells (NSCs) as a model cell line.
Even though previous studies have suggested that Hh is a mitogen in vitro for neural stem cells, our data indicate that Hh activation can not only increase the number of stem/progenitor cells in vivo, but in doing so shifts the balance of RG cell neurogenic divisions.
(A ) Schematic overview of the in vitro human neural stem cell differentiation protocol.
In the present study, we investigated adiponectin receptor (AdipoR -mediated signAdipoR -mediateding a high-fat diet and in vitro usignalingal stem cells (NSCs).
In vitro, these same neural stem cells induced microglial activation and amyloid phagocytosis, suggesting an immunomodulatory capacity.
Recent work [29], [30] established conditions for the isolation and clonogenic in vitro propagation of neural stem (NS) cells derived either from ES cells or from embryonic and adult neural tissue.
This assay has previously been used for the in vitro study of neural stem cell self-renewal [ 19] and relies on the observation that neurosphere formation is initiated clonally by neural stem cells [ 5].
We also show that the regenerative response can be recapitulated in vitro by transfecting NSPs (neural stem progenitors) with a constitutively active EGFR, and that pharmacologically inhibiting EGFR in vitro abrogates the expansion of the NSPs observed subsequent to injury.
The patent covers an in vitro method of propagating neural stem cells from mammals so they mature into the three major brain cell types (called neurons, astrocytes and oligodendrocytes).
