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Bode, C. J. et al. In Vitro Models for Studying Trophoblast Transcellular Transport.
The Bakerian Lecture, 1977: In Vitro Models for Photosynthesis, Proceedings of the Royal Society A Mathematicall, Physical and Engineering Sciences, 362 (1710) 281-303.
Rousset, M. The human colon carcinoma cell lines HT-29 and Caco-2: two in vitro models for the study of intestinal differentiation.
Bovine primary cultured hepatocytes (CHs) are widely used in vitro models for liver toxicity testing.
Patterned adhesion of neurones and directed growth of neurites is the pre-requisite to establish meaningful in vitro models for the study of interactions and signalling between neurones.
In vitro models for studying cancer metastasis have thus relied heavily on the use of simple assay systems that do not allow expression of the full spectrum of interactions and events that occur during metastasis.
As demonstrated, multiple tiers of physiologically relevant tests are necessary to deduct any evidence on the quality and performance of in vitro models for the chosen placental research field (Table 1).
Thus, the selection of relevant in vitro models for testing is critical for successful antimicrobial validation testing.
Novel microfluidic systems have facilitated the development and optimization of in vitro models for exploring the complex pathophysiological phenomena that occur inside a microvascular environment.
Three-dimensional organoids derived from human pluripotent stem cell (hPSC) derivatives have become widely used in vitro models for studying development and disease.
We will review traditional and emerging in vitro models for personalized medicine, focusing on the technologies, microenvironmental components, and readouts utilized.
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