Sentence examples for vitro models allow from inspiring English sources

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Validated in vitro models allow extensive device testing prior to in vivo studies which limits the numbers of animals required to reach conclusions regarding efficacy and safety.

These in vitro models allow not only the study of the mechanism of endothelial transmigration, but also the determination of specific BMS attractants.

Moreover, in vitro models allow rapid conduct of complex experiments involving parallel manipulation of bathing media, addition of inhibitors and calculation of transport kinetics while minimising the use of animals.

Due to the complexity of hepatic FXR signaling, involving entero-hepatic communication and interplay with extrahepatic tissues [ 2], none of the current in vitro models allow to study FXR functions in full.

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In spite of the slowing down or blocking of PCO development with square optic edges, there is still a relevant clinical evidence of PCO [ 8, 9] and consequently a considerable interest in developing in vitro models allowing the clinician to understand the mechanisms of LEC proliferation.

Despite these limitations, data from the in vitro model allow the conclusion that a down-regulation of epithelial SLPI expression (either by H. pylori or siRNA) does not affect the expression of Progranulin in AGS cells.

The in vitro model allows larger N4 substituents than the SURVival model, but they must not bear positive centres in the region 15 16 Å from the nitro group.

The described in vitro model allows evaluation of potential agents for the treatment of DH at the clinically relevant cervical region of human teeth.

An in vitro model allowing measurements of cervical dentinal perfusability using a new artificial dentinal fluid as a perfusion medium containing a blue dye was presented.

The force of contraction of this EHT was up to fourfold higher after mechanical stimulation and the protocol was proposed as an in vitro model allowing morphological, molecular, and functional consequences of stretch to be studied under defined conditions.

With purpose to obtain an in vitro model allowing for further characterization of the metabolic features of ccRCC cells, tumor as well as normal primary proximal tubular cells from patients diagnosed with ccRCC were isolated and cultured.

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