Sentence examples for vitro model this from inspiring English sources
In agreement with our in vitro model, this result suggests that telomerase inhibition by PPARγ ligands is independent from PPARγ transcriptional activity and is effected by an unknown mechanism.
The ALP compounds investigated in this study are known to be well-tolerated in various pre-clinical trials [24] and to do little harm in normal cells in various in vitro models; this could be due to the fact that normal cells do not activate the PI3K/Akt pathway unless they are exposed to extracellular insults.
CD133 levels are highly correlated with cells' clonogenicity, as shown by in vitro models; this has led some to hypothesize that glioblastomas are derived from CD133+ cells, but it is well known that some glioblastomas are CD133− [ 5, 6, 20, 63– 63].
This observation suggests that in this in vitro model, the MBNL1 cell localization is unaffected by the expression of the pathological CUG expansions.
To study the regulation of POMC expression by Sirt1, we used the AtT20 cell line that has been shown to be a useful in vitro model for this type of studies [26], [27].
Previous in vitro model suggest this refers to an inherent property of spinal motoneurons themselves [ 21].
DSL-6A/C1 cells represent an in vitro model of this carcinogenic sequence.
The prostatic epithelial cell (PEC)/BMS co-culture system as described by Lang et al (1998) represents an ideal in vitro model for this purpose.
These two models are driven by different pro-angiogenic growth factors; bFGF drives the in vivo model and VEGF drives the in vitro model; despite this STX2484 was efficacious in both models.
To clarify the mechanism of anti-fibrotic efficacy in Yiqihuoxue treatment in vitro, we utilized the cell line of NIH/3T3 fibroblasts to establish an in vitro model in this study.
An exemplary experimental in vitro model where this mechanism has been implicated is the inhibition by andrographolide of the release of TNF-α from LPS stimulated macrophages [ 22, 51- 54].
