Sentence examples for vitro model the from inspiring English sources
In our in vitro model, the basal 1 h uptake of PSMA-binding peptide differed between castration-resistant cells and the androgen-sensitive cell line.
In the present work, the effects of heterogeneous airway obstructions on the distribution of air and helium oxygen were examined using an in vitro model, the two compartments of a dual adult test lung.
In our in vitro model, the de novo synthesis of Elk-1 within a single dendrite leads to a local enrichment of Elk-1 protein within this subcellular compartment.
Using PC12 cells, a cell line derived from the neural crest, as an in vitro model, the current study was designed to elucidate the mechanisms underlying D3T mediated Nrf2 activation and subsequent antioxidant protection in ethanol-exposed neural crest cells and other developing neuronal cells.
In order to validate this finding and determine the net directionality of A20's effect, we performed OxyBlots on whole cell lystate from primary derived rat hepatocytes that were subjected to 60 min. of hypoxia, followed by 120 min. of reoxygenation, as a way to in vitro model the oxidative stress imposed on hepatocytes, such as in the setting of LR or ischemia reperfusion injury.
From the in vitro model, the optimal dosage form of a drug can be designed and verified in vivo.
Through the use of in vitro models, the biology of the cells involved in bone remodelling has made important advances.
Our approach combines the use of two in vitro models, the 1C11 cell line and neurosphere cultures.
Therefore, in human in vitro models, the relevance of endotoxin as a confounder could be less significant than in mice.
Because of the limited metabolic capacity of the in vitro models, the biotransformation of a chemical in vitro may be minimal compared with that in in vivo systems.
Evaluating the integrity of the BCECs in these in vitro models, the TEER measurements increased in all cultures in consequence to stimulation with hydrocortisone, cAMP and RO-201724.
