Sentence examples for vitro model resulted from inspiring English sources

Pretreatment of MSCs with injured liver tissue in an in vitro model resulted in high expression of albumin, CK8, CK18, transaminase, and HNF1a compared to untreated MSCs, indicating that this pretreatment augmented the homing and hepatic differentiation abilities of MSCs (Mohsin et al., 2011).

Neutralization of GM-CSF in a 3D in vitro model resulted in a complete abrogation of tumor cell invasion 16.

Significantly, as the limitations and inaccuracies inherent in translating in vitro model results to in vivo equivalence are more widely documented, the use of experimental animal models is likely to increase.

In another in vitro model, trastuzumab treatment resulted in an Akt-negative feedback loop that perpetuated HER2 phosphorylation, leading to a decreased response to trastuzumab [ 61].

Positive functional data were defined as any in vivo or in vitro model, demonstrating results differing from the wild-type model.

In agreement with our in vitro model, this result suggests that telomerase inhibition by PPARγ ligands is independent from PPARγ transcriptional activity and is effected by an unknown mechanism.

10 A parallel shift in emphasis in the field of tissue engineering, from regenerative medicine applications to in vitro models, 11 has resulted in numerous new complex models of liver, lung, gut, skin, muscle, blood vessels, and other tissues.

In studies, applying indirect measures of protein turnover, in vitro models provide results that suggests that attenuated energy turnover and loss of muscle mass may be developed at hypoxia exposure due to a decrease in overall protein turnover rate [7] [10].

Findings in an in vitro model correlated with results obtained from the PBMCs of TRAPS patients.

Although there are similarities between their in vitro model and our results, the induction of cholesterol catabolism, the methylcitrate cycle and aspartate metabolism are not captured using such a method, highlighting the differences between using an in vitro model based on even long chain fatty acids as opposed to studying intracellular infection directly.

Nlrp3 inflammasome activation by large amount of ATP (5 mM, 30 min) in the presence of LPS constitutes an in vitro model as prolonged stimulation results in membrane disruption and cell death underlying the pathological impact of high ATP levels.