Sentence examples for vitro model leads from inspiring English sources

We previously could show that increased SERCA expression in our in vitro model leads to an improved force frequency relationship [ 17].

As a representative example, we observed that a 3-D in vitro model leads to an in vitro gene profile similar to that displayed in vivo for TP53 or CDKN2B only in Tum 06, for FasL only in Tum 07 or for KRT8 only in Tum 25.

In our studies presence of various P. hysterophorus extracts in LPOI in vitro model led to reduction of adduct formation indicating their lipo-protective potential.

Furthermore, differences between in silico and in vitro models led to predictions for a role in wound‐induced signaling events in urothelial cell cultures, showing the benefits of an iterative modeling and experimental work cycle.

The data presented in this study are from a controlled in vitro model, which leads to limitations in transferring the results to clinical practice.

To investigate which of the three in vitro cell models led to the gene profile closest to that observed in vivo for a specific gene and a specific tumour, the three values were compared by variance analysis and the multiple Bonferroni t-test if variance analysis was significant.

CD133 levels are highly correlated with cells' clonogenicity, as shown by in vitro models; this has led some to hypothesize that glioblastomas are derived from CD133+ cells, but it is well known that some glioblastomas are CD133− [ 5, 6, 20, 63– 63].

Furthermore, others have reported vessel occlusion following Dll4-inhibition in an in vitro model, where HUVEC sprouting in fibrin gels led to the loss of lumen-like structures, which were replaced by densely packed endothelial cells [21].

In our in vitro model, the de novo synthesis of Elk-1 within a single dendrite leads to a local enrichment of Elk-1 protein within this subcellular compartment.

This phenotypic specificity led us to develop a human neuronal in vitro model for HSPs using hiPSCs derived from SPG4 patients.

In an in vitro model of peritoneal wound healing [ 42], mechanical disruption of HPMC monolayers led to upregulated HAS2 transcription together with an increase in HA synthesis [ 33].