Sentence examples for vitro model have from inspiring English sources
The determination of glutathione content and the parallel plate flow chamber in vitro model have been described in detail previously (8, 18, 19).
An oncogenic role for JCV has been demonstrated in several animal studies including rodents and primates (reviewed in [30]), but the lack of an adequate in vitro model has hampered our understanding of the role of JCV in human cancer.
As shown in Figure 3B E, the signature derived from the in vitro model has an ability to accurately predict the status of human primary breast cancer samples from three independent datasets, validating the predictive ability of the signature.
This in vitro model has limitations in that cells are derived from naïve mice rather than from tumor-bearing mice.
A new in vitro model has been developed for investigating extravascular diffusion of therapeutic agents in tumour tissue.
Interestingly, a similar observation about a peak effect of 50% xenon in the same in vitro model has been made by Coburn and colleagues.
Clearly, this simplified in vitro model has other inherent limitations since it neither includes true infection nor simulates all aspects of sepsis in an intact organism.
This human-derived in vitro model has been used worldwide by chemical, pharmaceutical and consumer product companies in testing approaches to reduce or replace animal testing [ 10, 11].
Nevertheless, the in vitro model has been useful for identifying and studying mechanistic details of apoptosis induced by agents that suppress neuronal excitability in vivo.
This in vitro model has been extensively characterized in several previous studies where the phenotype and expression patterns of a variety of lineage markers of neuronal progeny derived from these NPCs have been examined in detail.
This in vitro model has been used to study mechanisms of cancer aggressive behavior, metastasis, and poor prognosis [ 42], and has been used as a tool to screen therapeutic agents for their anti-metastatic property [ 30, 43].
