Sentence examples for vitro model data from inspiring English sources

As a further control, we have tested the migration of A375 (a commercially available melanoma cell line) in our model and we found similar transmigration ability if compared to what was previously reported by other authors for the same cell line in a similar in vitro model (data not shown) [ 53].

We found no enhancement of growth inhibition following treatment with a combination of ICR62 with afatinib or gemcitabine or erlotinib in these in vitro models (data not shown).

Additional microarray experiments performed in parallel with NM reference strain revealed similar gene expression patterns in vivo compared to in vitro models (data not shown) indicating that the trends described by the Dutch 602 outbreak field strain are likely to prove relevant to other C. burnetii strains more generally.

Therefore, there is an urgent need to validate existing in vitro models using data from animal models, although these animal models do not fully simulate the physiology of humans.

This study provides an in vitro model and baseline data on future developments of new strategies for salivary gland regeneration and replacement.

Still, due to the limitations of the chosen in vitro model system our data need to be interpreted carefully.

Although we have not measured plasma hepcidin concentrations or directly measured macrophage iron in this study, in vitro and animal model data indicates iron influences the development of TB and iron-loaded macrophages promote Mycobacterium growth [ 23- 27].

Convincing evidence from both in vitro and mouse model data suggest that statins can be used as a potential cancer therapeutic depending on the type of cancer cell, but the effects of statins on ML cells and related mechanism have been veiled.

The metric for the module (MPA) of size M is defined as, (3) s → 1 = 1 M ∑ i ∈ M P A σ i z → i where z → i denotes the z-score normalised (mean zero and unit variance) expression profile of gene i across the tumours and σ i denotes the sign of pathway activation (from the in-vitro model signature data), i.e σ i = 1 if upregulated upon activation, σ i = -1 if downregulated.

A strong relation (R2 = 0.99) was obtained between the disappearance data from the donor compartment of the in vitro model and the disappearance data from the synovial fluid after intra-articular administration of DTZ.

In agreement with our in vitro data, our mouse model data indicated that the down-regulation of SIRT3 in OSCC cells significantly inhibited tumor growth in vivo (Fig. 5B).