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Hence, as stressed also by MTT proliferation assay, our in vitro model confirmed the starting hypothesis regarding the possibility to use Wharton's jelly in composite scaffolds that mimic articular cartilage.
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The results of our in vitro model confirm the previously described impacts of miR-126 on normal and inflammatory events.
Following this, an in vitro wound model confirmed that PLNs functionalized with both wound adhesive and activated platelet aggregatory peptides formed clots more efficiently than PLNs functionalized with adhesive only or aggregatory only peptides.
By ultrastructural analysis of the same in vitro model, we confirmed that GluRδ2 regulates presynaptic differentiation of granule cell axons, although it is unclear whether GluRδ2 induces the formation of PF synaptic contacts in vivo.
Furthermore, in this in vitro model, we confirmed the controlled release of CXB into the medium from 0.1 mg/ml and 1 mg/ml CXB-loaded hydrogels, respectively.
This in vitro model further confirmed the docking results that WA might enter the HRas-RasGAP complex to interfere with the interaction of HRas-GTP and RasGAP.
An in vivo xenograft model confirmed the in vitro data and showed dramatic reduction in tumor mass accompanied by reduced vascularity and increased necrosis within the tumor, suggesting that the reduced tumor burden in the treated mice may in part be due to reduced angiogenesis.
Findings in that in vivo model confirmed the in vitro data [ 14] and pointed to the fact that p27 inactivation via degradation appears to switch from being mitogen dependent in G1 to mitogen independent in the DNA replication phase of the cell cycle.
An immunocompromised mouse model confirmed that the in vitro resistance corresponded with treatment failure.
The toxicological model of 3D-reconstructed cornea epithelial model confirmed the cytotoxicity of BAC-containing solutions with a better approach of what exists in vivo or in vitro.
The low unspecific background of this new in vitro model system was confirmed by phase contrast microscopy and RICM.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com