Sentence examples for vitro model all from inspiring English sources
Finally, as with any in vitro model, all findings might not translate back to the in vivo setting, and therefore will require validation in an animal model.
In the in vitro model, all tested CM induced a dose-dependent phosphorylation of JNK1/2 and p38.
Additionally, subnetwork 57 includes four drugs, clomipramine, danazol, nitrofurantoin and nitrofurantoin with 8 hours, medium or high dose condition in in vitro model, and all of them are most-DILI-concern defined by LTKB.
Studying the life cycle of HBV has been complicated mostly due to the lack of suitable in vitro models recapitulating all steps of the viral life cycle in hepatocytes and the difficulty of modeling physiologically intact host cells for HBV replication.
As there is no one in vitro model which can mimic all properties of the in vivo BBB, developing more reliable models remains challenging [ 4].
Optimizing the TJ tightness of hCMEC/D3 cell monolayers still remains a major challenge in order to provide an in vitro model that might recapitulate all the characteristics of human BBB, encompassing permeability restriction with appropriate molecular exclusion and functional efflux and influx transport systems.
Fourth, current in vitro models are almost all static, while in vivo exposure is dynamic.
Equipped with this kind of intimate understanding of the structure-switching property relationship, we are now better able to design and develop new dynamic surface materials for biomedical applications ranging in diversity from but not limited to in vitro model systems for fundamental cellular studies, all the way through to sophisticated drug delivery systems.
Since aberrant IGFBP7 expression was observed in a variety of neoplasia and was relevant for prognosis in T-ALL, we investigated the functional role of IGFBP7 in Jurkat and Molt-4 cells as in vitro models for T-ALL.
We used an in vitro model to manipulate experimental conditions while controlling for all other variables.
On the other hand, deletion of SP_1922 totally abolishes all the adhesion seen in this in vitro model.
