Sentence examples for vitro into the from inspiring English sources

We found that introduction of mutations that reduced actin binding in vitro into the isolated C-terminal Talin-ABD impaired actin binding in vivo.

We injected brain-derived FTLD-TDP-GRN extracts, with proven seeding activity in vitro, into the brains of previously characterized Dox-regulatable transgenic (Tg) mice expressing a cytoplasmic NLS mutant of human TDP-43 (hTDP43NLSm) in forebrain neurons (CamKIIa-hTDP43NLSm 25,26. CamKIIa-hTDP43NLSm 25,26

Another approach to directing integration is to fuse integrase with a sequence-specific DNA-binding protein, which results in a bias of integration in vitro into the recognition site of the fusion partner.

Deletions of up to 12 N-terminal residues as well as random substitutions of the second, third and fourth residues yielded trimers that failed to incorporate in vitro into the T4 9−-particles and were not able to convert them into infectious virions.

The first example of clinical cartilage tissue engineering was performed in 1987 when a knee with an articular cartilage defect on the femoral condyle was treated by implanting the patient's own chondrocytes that had been expanded in vitro into the defect in combination with a covering mechanical membrane the periosteum.

Cu uptake in vitro into the apoprotein of azurin expressed in Escherichia coli fractionates the Cu isotopes, and the azurin (δ65Cu -1.64) was enriched in the lighter isotope relative to the source material (δ65Cu -0.11) [9].

Membrane protein folding is complicated by the need to recreate a suitable membrane mimetic environment in vitro into which the protein can fold [47].

When mouse embryonic stem cells were coaxed, in vitro, into becoming the motor neurons, TAF9B was selectively up-regulated.

Conceptually, irritant contact dermatitis (irritation) and allergic contact dermatitis (ACD) in man should provide the ideal platforms to launch in vitro toxicology into the pantheon of in vitro testing assays.

Thus, we preliminarily tested the capability of recombinant isomin to assemble in vitro into filaments, using the standard re-assembly conditions described for other IF proteins [ 24].

These cells have been shown to differentiate in vitro into at least the adipogenic, chondrogenic, myogenic, neurogenic, and osteogenic lineages in the presence of specific induction factors.