Sentence examples for vitro germ cell from inspiring English sources

In vitro germ cell differentiation was confirmed with the detection of haploid cells.

However, little is known about the differentiation markers and culture conditions for in vitro germ cell differentiation from ES cells in primates.

Therefore, it is very important to develop a suitable protocol to induce in vitro germ cell differentiation from monkey ES cells before non-human primate ES cells can be used as a model for in vitro differentiated germ cells.

von Meyenn, F. et al. Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification.

Although Rif1 is highly expressed in totipotent and many pluripotent cell types (zygotes, cleaving embryos, ESC lines maintained in vitro, primordial germ cells), it is downregulated in the ICM of the blastocyst [ 54].

5caC: 5-carboxylcytosine; 5fC: 5-formylcytosine; 5hmC: 5-hydroxymethylcytosine; 5mC: 5-methylcytosine; (e): embryonic day; AID/APOBEC: activation-induced deaminase/apolipoprotein B editing complex; BER: base excision repair; DAB: diaminobenzamine; IHC: immunohistochemistry; iPGC: in vitro primordial germ cells; PGC: primordial germ cells; TDG: Thymine DNA Glycosylase; TET: ten-eleven translocase.

When exposed to high levels of estrogens in vitro, primordial germ cells (PGCs, the embryonic precursors of gametes) start transcription of C-kit ligand (KITLG), and the accumulation of this growth factor eventually transforms PGCs into tumorigenic cells [ Moe-Behrens et al., 2003].

However, it remains unclear whether primate ES cells including those from humans can undergo gametogenesis through meiosis in vitro, although immature germ cell differentiation from primate ES cells has been reported [5], [6], [7].

Furthermore, our data indicated that in vitro ESC-derived germ cell differentiation initially followed an endogenous timeline.

Similarly, MEHP exposure in vitro causes apoptotic germ cell loss in human fetal testis explants (Lambrot et al. 2009; Muczynski et al. 2012).

The need to develop methods for the production and in vitro cultivation of germ cell lines for genetic manipulation is emphasized [ 89].