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The morphology, differentiation potential, cytokine responsiveness and kinetics of gene expression of EPL cells are consistent with the formation of an in vitro equivalent of the embryonic primitive ectoderm, or epiblast [37] [39].
Thus we compared IFNγ production in the two populations in response to specific CFP-10 antigen [34] as well as to non-specific Ag85A [35], latency associated HspX [17] and the mixture of culture filtrate proteins (CFP) as an in vitro equivalent to TST.
Instead such neurons only become mechanosensitive 48 h later, which is the in vitro equivalent to E13.5.
These BL-CFCs display both endothelial and haematopoietic potential and are thought to represent the in vitro equivalent of the haemangioblast (Choi et al, 1998).
In vitro, equivalent Phortress-generated adduct species are represented by peaks 16 and 19 in MCF-7 and IGROV-1 cells, respectively.
Next, from the optimal concentrations of tPA and D-penicillamine in vitro, equivalent dosages were administered to healthy Balb/c mice to explore upregulation of circulating angiostatin levels.
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(A ) Schematic of early mouse development and their in vitro equivalents.
Differentiation of these reporter lines was assessed by quantitative RT-PCR (q-RT-PCR), which confirmed that these cells pass through the in vitro equivalents of specific developmental stages, including PS, APS (or mesendoderm), and ADE, thereby recapitulating in vivo development.
Composites with nano-sized TCP particles degrade more homogenously in vitro than equivalent composites with micro-sized particles.
Using an in vitro skin equivalent model strong evidence was provided for a critical and specific function of c-Jun and JunB in mesenchymal epithelial interaction in the skin by regulating the expression of interleukin-1 (IL-1 -induced IL-1 -inducedgrowth factor (KGF) and GM-CSF IL-1 -induceds.
In the present studies we sought to determine whether expression of H-ras in skin keratinocytes would affect these parameters during the establishment and maintenance of an in vitro skin equivalent.
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