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All in vitro data are expressed as means ± SEM, all in vivo data as means ± SD.
Similarly, when in vitro data are used, the preferred procedures are identified.
Together with chemical information in vitro data are used to predict in vivo toxicity and to prioritise animal testing.
Among the 744 chemicals in the combined dataset with in vitro data are 693 without information about in vivo mammalian long-term reproductive toxicity, 335 of them with structural alerts and 358 without structural alerts.
This would suggest that the stem cell in these diseases is abnormal and could be cured by replacement of a normal stem cell although more in vitro data are required in this area.
While in vitro data are available on the possible mechanisms of action of IgM-enriched immunoglobulins, the results of the in vivo experimental studies are non-univocal and, overall, unconvincing.
These in vitro data are related to the research article, entitled "Identification of a bioactive core sequence from human laminin and its applicability to tissue engineering" (Yeo et al., 2015) [1].
In vitro data are in contrast to the in vivo findings of abnormal accumulation of glycogen.
Our in vitro data are in close agreement with our recent in vivo findings.
All in vitro data are from at least three independent experiments.
In vitro data are reported as mean ± SD of at least three experiments.
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