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The aim of this work was to develop and validate an experimental method to replicate spontaneous fractures in vitro based on clinically relevant loading.
The performance of existing and new structural alerts was evaluated with the collected dataset of estrogenic and androgenic activities in vitro based on the number of substances with endocrine activity that contain the structural alert ("true positives") relative to the number of substances without endocrine activity that contain the same structural alert ("false positives").
The compound 2,3,5,4′-tetrahydroxystilbene-2-O-β-d-glucoside (THSG) can induce CSC proliferation in vitro based on our previous study, so we aimed to study the induce effect of THSG on CSCs-transplanted MI rat in vivo.
For studying the angiogenesis process in vitro based on endothelial cells, numerous assay models have been applied.
ERAP1 has unique properties for an aminopeptidase being able to trim peptides in vitro based on their length and the nature of their C-termini.
For this purpose, we derived wildtype, heterozygous Dazl+/− and Dazl−/− null mESC lines and directly compared germ cell differentiation, in vivo and in vitro, based on knowledge of landmark events and diagnostic gene expression patterns (Figure S1; adapted from [34]).
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Our objective was to develop a rapid and successful method for in vitro propagation based on an initial in vitro asymbiotic seed germination step that achieved high percentages.
Only the IV bolus dose reached the in vitro IC50 based on free plasma concentrations.
The biomaterial toxicity is measured through in vitro tests based on motoneuron survival and neurite growth on copolymer substrate.
The antioxidant potential was investigated using in vitro methods based on ferric/phosphomolybdenum reducing antioxidant power and DPPH/ABTS radical scavenging assay.
Cell culture experiments are usually performed as in vitro studies based on 2D seeding and characterization (light microscopy).
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