Sentence examples for vitro although the from inspiring English sources

We have demonstrated that HBK001 can inhibit DPP4 enzymatic activity in vitro although the inhibitory potency is weaker than linagliptin.

Similarly, various fluorescently labeled lipid analogs have been used to study membrane organization and function in vitro, although the biological activity of these probes in relation to their native counterparts often remains uncharacterized.

CaMKIV does not phosphorylate RORalpha or its ligand-binding domain (LBD) in vitro, although the LBD is essential for transactivation.

Due to poor expression and stability of the Tob W93A mutant, we were unable to test the interaction of this mutant with CNOT7 in vitro, although the mutant expressed in mammalian cells for subsequent interaction assays in vivo.

Consistent with the immature phenotype of Foxn1Δ/Δ peripheral T cells, some CD4+ T cells couldn't completely be activated under anti CD3 stimulation in vitro, although the CD8+ T cells appeared more normal than CD4 T cells (Fig. 5D).

We showed that a corrected full-length CD18 is produced as a result of gentamicin treatment both in vivo and in vitro, although the protein is either dysfunctional or mislocalized.

A study investigating the distribution of hyaluronidases in a diverse collection of S. suis isolates identified fewer than 30% exhibited hyaluronate lyase activity in vitro, although all the isolates tested (n. 309) contained the hyaluronidase gene (hly) [101].

These regional phase differences were largely maintained across the first three cycles in vitro, although changes in the phase of regions within the central SCN were evident (Figure S2).

We found that Akt phosphorylates Bcl-w in vitro, although not with the same efficiency as histone H2B (Figure 4A).

Similarly, hESCs can also be cultured in vitro, although they require the activation of fibroblast growth factor (FGF2) and TGFβ/activin/Nodal pathways for maintenance.

Profiles from the two in vivo experiments are also closest to each other (r = 0.41) and substantially different from both in vitro experiments, although the Valouev et al. nucleosome map is also significantly correlated with the Rsa I in vitro profile (r = 0.38).