Exact(6)
SF-36 scores also displayed a significant difference between treatment groups for both the aggregate physical component (median change = 9.25; p = <0.0001) and the aggregate mental component (median change = 4.26; p = 0.0045) and for all domains except vitality (Table 3).
Patients with chronic CRPS displayed significantly decreased health related quality of life in seven of the eight dimensions of the SF36 (p<0.0015), with the only exception of the dimension vitality (Table 6).
The correlation between the GHQ-12 and the VS scores was investigated and as expected a significant negative correlation emerged (r = -0.71, P < 0.01), indicating that those who were more distressed showed lower levels of subjective vitality (Table 2).
However, since there is no trend of basal OCR, or any of the other OCR parameters, with vitality (Table 1 and Figure S1) we feel that the N of 40 we have is sufficient, in that more participants would not change the null OCR-vitality association.
Within the severe subgroup, there was a significant difference (P < 0.05) in the mean change of the SF-36 scores from baseline to endpoint between the duloxetine and placebo groups on the health outcome measures of the SF-36 mental component summary; bodily pain, general health, mental health, physical functioning, role-emotional, role-physical, social functioning, and vitality (Table 2).
Patients had lower SF-36 health status scores for bodily pain (p=0.03) and health compared with 1 year earlier (p=0.02), but no differences existed for physical function, role limitations due to physical health, general health, or vitality (Table 2).
Similar(54)
Greater symptom burden was linked with both reduced mental health and lower vitality (Tables 4 and 5), flagging the importance of considering nurses' general health status and factors potentially influencing this.
FSS, VAS, FACIT-F, vitality, see Table 1 legend.
We found that ROS production was inversely associated with vitality score (Table 1; Figure S3).
None of the OCR or ECAR parameters had a significant association with vitality score (Table 1: Figures S1 and S2).
Aggregate data showed significant positive changes in SF-36 scores in the Mental Health, Role Limitations due to Emotions, and Vitality domains (Table 2).
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