Sentence examples for vital substrate for from inspiring English sources

Haemolysis also releases arginase 1 into plasma, depleting the vital substrate for NO production, arginine [ 42].

Following activation of the initiator caspase-8 or -9, the two pathways converge on the activation of caspase-3, which finally execute the death process by cleaving various vital substrates required for cell survival and maintaining the integrity of the genomic DNA [ 5].

The development of targeted therapies against mTOR, a vital substrate along this pathway, led to the approval of allosteric inhibitors, including everolimus and temsirolimus, for the treatment of breast, renal, and pancreatic cancers.

Anesthetic agents alter microcirculation, influencing tissue oxygenation and delivery of vital substrates.

PMCAs are vital caspase substrates for the subroutine of the death program leading to secondary necrosis.

The two domains of sACE contain many conserved residues, which are vital for substrate and inhibitor binding (Table 4).

All three ATPases are vital for substrate transfer from VirB11 to the presumptive inner membrane channel complex.

In the acute phase, this catabolic response may be beneficial, providing amino acids for hepatic gluconeogenesis (supplying substrate for vital tissues such as the brain and immune cells) and for synthesis of proteins involved in immune function and in the acute-phase response.

Given longer incubation periods, we predict that all aerobic samples would reach the same total glucose production, indicative that there is a given fraction of the substrate for which this activity is vital.

Phospholipids are vital part of biomembrane rich in PUFA, which are susceptible substrate for free radicals such as O2- and OH radicals [ 42].

Furthermore, the type of storage carbohydrate is of vital importance if the biomass is to be used as a fermentation substrate for fungi.