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All turned out to have a mutation that disrupted this vital gene.
And in another world, only slightly in the future, a vital gene is identified, ensuring optimism for all.
Dr. Cooke and Dr. Hogenesch said they were less interested in the precise number of human genes than in making sure they had the full set, however many it might be, since researchers trying to understand some aspect of the body's function could be led astray if some vital gene was missing from the catalog.
The researchers determined that 176 of the human genes allowed yeast to survive the loss of a vital gene.
Even a 'mild' slow-down of the search mechanisms may cause numerous diseases by delaying the synthesis and/or turnover of vital gene products and moving them out of a required synchrony.
Existence of this systemic RNAi vital gene transcript in all larval developmental stages and four tissues of S. exigua may account for the systemic RNAi effect in this insect after ingestion of dsRNA.
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Extensive research on the genetic basis of human diseases with complete sequencing of human genome has revealed many vital genes as possible targets in gene therapy programs.
In this respect, metabolomics, providing molecular dissection of metabolic pathways for identifying vital genes, also offers a means for specific dis-functioning of these genes to cause mortality in individual insect species.
The expression of a number of vital genes was observed to be affected in absence of PykA, showing that mtPykA is important for the cell but not indispensable.
These molecules can form adducts with cellular DNA, leading to mutations in vital genes like Ras, p53, and Rb [2], [3], [4].
Retrotransposition, however, also comes with the danger of randomly damaging vital genes.
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