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The replacement of renal function by hemodialysis (HD) demonstrated for the first time that at least the most vital functions of a complex organ could be replaced by a man-made device.
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For the past century, it has also performed the vital function of a scientific and medical research tool.
To our knowledge, this is the first genetic demonstration of a vital function of a distinct protease that first becomes apparent in the absence of a second protease, and thus underlies the importance of the new emerging protective roles of proteases (Lopez-Otin and Matrisian, 2007).
Due to the enormous complexity of a cellular system, where many processes and interactions at different levels inside a cell work in harmony to assure the vital functioning of a cell, we need to understand key properties of biological systems like its robustness or modularity [ 2, 8] in order to enhance our understanding of complex diseases.
The evolutionary advantages of temporary ribozyme promiscuity are obvious, if different catalytic functions need to be present at the same location for a vital function of an evolvable system to work, even if the cost of catalytic promiscuity is paid in reduced enzyme activity, as is the case for ribozymes in general.
Promoting a country's art, music and literature is a vital function of any consulate, and where more so than in this city?
Public health awareness and risk communication form a vital function of any health authority.
Finally, the cell cycle together with DNA metabolism and cell death, which are vital functions of living in a cellular population, were also enriched.
To gain insight into the vital functions of FUS and how a loss of FUS function impacts cellular homeostasis, FUS expression was reduced in different cellular models through RNA interference.
NGF is a neurotrophic factor that regulates a number of vital functions of the neurons including survival, growth, proliferation, and differentiation [ 10].
Volatile metabolites released by microorganisms produce an inhibitory, sometimes bactericidal, effect on the vital functions of bacteria.
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