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Construction firm Jarvis, which holds the contracts for both track renewals and track maintenance on the line, said the points in question passed visual safety inspections the day before Friday's crash.
APPLICATION TO CLINICAL PRACTICE: Assessed visual safety of tadalafil/sildenafil administered daily over a prolonged period.
A better understanding of the relationship across these variables was expected to lead the University to embrace policies to better manage inbound delivery flows to the campus, reducing the visual, safety, congestion, economic and operational impacts.
Aslef General Secretary Mick Whelan said: "The driver, on a final visual safety check, saw a tiny hand reaching up from the track - the train remained in position and a young life was saved.
The total duration of the fMRI experiment was 25 min. Each trial in the relief task started with a 6-second pain cue, paired with a subsequent 5-second painful heat stimulus (individually calibrated to induce intense pain) or a visual safety cue displayed for 5 seconds (figure 1A).
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Main outcome measure Ocular safety (ocular examinations, visual function tests, participants' reports of adverse events, and visual disturbance questionnaire completed by investigators) by treatment group at 12 weeks, 24 weeks, 18 months, and yearly.
Firstly, because ocular safety, including visual function, was not the primary objective of this phase III study, the sample size calculation was not based on ocular end points.
The ocular safety and visual function evaluation was an additional component based on newly emerging ocular safety signals with the use of sildenafil on an as needed basis for the indication of erectile dysfunction.
No clinically significant, treatment-emergent abnormalities in vital signs were noted in either treatment group during the study, and there were no clinically important between-group differences in ocular safety assessments or visual field examination findings.
37 38 To evaluate potential effects on visual function and the ocular safety profile of sildenafil during chronic oral use, the pivotal placebo controlled trial of sildenafil for the treatment of pulmonary arterial hypertension and its open label extension included ophthalmic examinations and assessments of visual function.
To evaluate the visual outcomes, safety, stability, efficacy, and predictability of laser in situ keratomileusis (LASIK) to correct myopia using a high-repetition-rate excimer laser with an optimized ablation profile.
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