Note that, for the selective decoding model, we do not consider situations in which correlated noise between the two pools depends only on vestibular or visual heading preferences.
In contrast, studies that measured heading tuning with the eye and head at different static positions have revealed an eye-centered reference frame for visual heading tuning in VIP (Chen et al., 2013, 2014).
In the visual condition, this correlation structure will lead to an opposite cell responding more when the animal chooses its non-preferred visual heading, thus producing a CP <0.5.
To investigate the effect of rotations on the visual heading tuning of VIP neurons, we presented visual stimuli simulating eight directions of translation in the horizontal plane and two directions of rotation.
In contrast, if correlated noise depends on the similarity of visual heading preferences, then the pattern of results will be reversed for the vestibular and visual conditions, which is clearly inconsistent with the experimental data.
As shown previously, neurons in area MSTd have vestibular heading tuning that can be either congruent with or opposite to their visual heading tuning (Gu et al., 2006, 2008).
On the other hand, if responses of model neurons were decoded with respect to their visual heading preferences, the pattern of CPs across stimulus conditions would reverse and would be incompatible with that observed for MSTd neurons.
DOI: http://dx.doi.org/10.7554/eLife.02670.005 10.7554/eLiFigure70.006 Figure 2 figure supplement 2. Predictions from a variant of the selective decoding model in which responses are decoded according to the visual heading tuning of each neuron, instead of the vestibular tuning.
We showed previously that congruent and opposite cells have CPs with opposite polarities in a visual heading discrimination task (Gu et al., 2008; Chen et al., 2013), and we suggested that this may result from selectively decoding both congruent and opposite cells according to their vestibular heading preferences (Gu et al., 2008).
Another visual effects head who wanted to remain anonymous, said: "Everyone was in awe of what they achieved" before adding: "It is a sad day when such a respected company faces issues like this.
