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The visible differentiation of cells is only the last of a progressive sequence of states.
Anaplasia is a loss of visible differentiation that can occur in advanced cancer.
Oct4 downregulation resulted in visible differentiation of hPSC colonies (Figure 1A D).
PSG2 and KRT18 expression are among the first signs that a blastomere has lost its totipotent competence, prior to any visible differentiation [ 33].
Furthermore, porcine iPSCs from these conditions were placed into MEF feeder conditions, and there was no visible differentiation in addition to those that were maintained in the traditional feeder system and 1(i)).
Levels of genetic differentiation among the three geographic regions inferred by Structure were significant (D and FST) and the following trend was visible: differentiation was largest between the "Turkish" and the "Eastern" clusters (0.31; 0.26**), and lowest between the Turkish and the "Western" clusters (0.22; 0.15**) (supplementary table S5, Supplementary Material online).
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Despite a lack of visible morphological differentiation, the two domed lineages are as genetically distinct from each other as from tortoises occurring on other islands.
At day 3, multinucleated myotubes are clearly visible and differentiation continues thereafter.
As has been summarized in this review, the regulation by DSXM or DSXF on dimorphic trait development is diverse and extends to all aspects of, often visible, sexual differentiation like the branches on the tree.
Individual brushstrokes sometimes remain visible, although the differentiation in the brushwork is extraordinary.
As programs like these gain wider recognition, businesses may consider engaging with "data rating agencies" to give credence to their assessment, and harness them as a more visible source of differentiation and brand enhancement.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com