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Infected giant viruses grow abnormally, with thicker capsules, and produce fewer progeny, La Scola and his colleagues report in the 7 August issue of Nature.
Type II viruses grow readily in vitro (28).
Type I viruses grow poorly in tissue cultures and show virtually no neutralization with anti– canine coronavirus sera (27).
Earlier studies have shown that Us11-null viruses grow normally in vitro and are slightly attenuated in vivo, suggesting that the function of Us11 may be compensated by the extant ICP34.5 [ 46, 47].
Here l is the immunity decay rate (x → y flow), e is the immunity acquisition rate; d is the death rate of viruses, M is the virus reproduction rate; b is the encounter rate coefficient; the growth rates of immune and sensitive hosts are equal to 1. Model (1) for a = 0 describes a situation when immune and sensitive hosts in the absence of viruses grow according to the Malthusian model.
Similar(54)
Our results showed that all the tested H5N1 vaccine viruses grew to high titers in eggs.
The structural protein patterns of three of these viruses, growing to a high titer, appeared very similar but not identical.
After both Dr. Vogt and Dr. Dulbecco joined the Salk Institute, they continued their research together, experimenting with animal viruses grown in cultures.
Differences were noted when cultivating the cells at 33 oC or 37 oC with human H5N1 viruses growing to higher titers at 33 oC.
He says that his fascination with viruses grew, partly for personal reasons.
The modified viruses grew like wild type TB4-wt even at the low MOI of 0.01.
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