Exact(39)
The following experiments of the virus virulence and cytokine induction in mice were also performed.
Open image in new window Figure 1 Virus virulence, cytokine induction and phylogenetic analyses of Guangdong H7N9 virus.
The effects of such vaccine-driven evolution on virus virulence and transmissibility in unvaccinated animals have yet to be determined.
Some amino acid mutations were discovered to be crucial for virus virulence (Yang et al., 2014), but how they affect the viral virulence remained unclear.
It is considered as unlikely that the JE live vaccine SA14-14-2 reverts itso its parental virus virulence by random amino acids mutations.
A comparative pathogenicity study in pigs (n = 10) revealed that the nsp2 deletion had no effect on virus virulence, and the restored nsp2 sequence in the VR2385-R viremainsainstablele during virus replication in pigs.
Similar(21)
That was not based on the virus's virulence.
How many would die would depend on the virus's virulence.
For instance, publishing only "specific insights" instead of the whole genome, like the mutations responsible for the virus's virulence, is no less subject to misuse, while their demands for policies for controlling dissemination of dual-use information do not consider recent efforts in this area by scientific organizations, government and journal editors.
This built on work by Australian Frank Macfarlane Burnet, who showed that the virus lost virulence when it was cultured in fertilized hen's eggs.
In our experiments we have performed short-term evolution passages measuring the virus accumulation, virulence and infectivity rate.
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