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It is anticipated that the development of virus resistant crops carrying multiple resistance-conferring gene sequences will be further facilitated by progress at unraveling underpinnings of virus host interactions, and at determining the sequence of more crop genomes.
The T1 progeny transgenic plants were virus resistant, confirming that the resistance phenotype was heritable.
Alarmingly, virus resistant to one short hairpin RNA (shRNA) also exhibits cross-resistance to a different shRNA, which targets a distinct and spatially distant region to which the virus has not been previously exposed.
Asked about that, Dr. Schuchat said the same mutation had also been found in mild cases in several countries and it did not make the virus resistant to vaccine or to treatment with drugs like Tamiflu.
Mutations in some strains of influenza A virus can render the virus resistant to amantadine; however, these mutations do not appear to increase virulence.
Here, we extend the model to account for therapy and the emergence of virus resistant to antiretroviral drugs.
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It was insect-resistant, not virus-resistant, though one version did include resistance to a virus.
Natural sources of resistance have been exploited extensively to develop virus-resistant plants by conventional breeding.
The EPA regulates transgenic plants that are engineered for pest resistance, for example Bt insect-resistant or virus-resistant plants.
Success in developing virus-resistant herbaceous crops through genetic engineering led us to investigate this approach for resistance to PPV.
Moreover, screening for virus-resistant mutants in a single bacterial culture has revealed many loci that carry resistance mutations to viruses [ 34].
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