Sentence examples for virus replicon from inspiring English sources
As a result, the chimeric CSF-JE virus replicon particle (VRP), rv187delE2/JEV-tE, was rescued.
Prodrug 2 displays improved in vitro antiviral activity against the hepatitis C virus replicon and influenza virus.
Virus replicon particles (VRP) are genetically engineered infectious virions incapable of generating progeny virus due to partial or complete deletion of at least one structural gene.
A trans-complemented chimeric CSF-JE virus replicon was constructed using an infectious cDNA clone of the CSF virus (CSFV) Alfort/187 strain.
Virus replicon particles are capable of infection, genome replication and gene expression, but are unable to produce progeny virions, rendering their use inherently safe.
We tested select heterologous prime-boost combinations and identified recombinant vesicular stomatitis virus (rVSV) and recombinant Venezuelan equine encephalitis virus replicons (VRP) as the most synergistic regimen.
Specificity of the interference was shown by demonstrating that silencing proteasome subunits did not interfere with Venezuelan equine encephalitis virus replicons.
In this study we investigated the feasibility of influenza A virus replicons for transient expression of recombinant proteins in mammalian cells.
Viral vectors in which this technique has been successfully used to control transgene expression include Dengue virus replicons [12], Alphaviral replicons [13], Lentiviral vectors [14] and Adenoviral vectors [15].
Immunogenicity in mice to NiV glycoproteins has been reported recently using two vectored approaches for gene delivery; one using Venezuelan equine encephalitis virus replicons [33] and the other involving inoculation of a mix of two complementing defective vesicular stomatitis virus (VSVΔG) vectors, one for expressing each of the two NiV glycoproteins [34].
