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Senescence has also been described to be associated to the progression of fibrosis in hepatitis C virus recurrence after liver transplantation, where a correlation has been observed between ischemic necrosis and replicative senescence on the revascularization biopsy, suggesting that livers containing senescent cells may be more sensitive to ischemia [10].
These cells represent an extrahepatic reservoir that can be implicated in virus recurrence and persistence [ 8, 9].
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The following MeSH search terms were used: "herpes simplex"; "herpes simplex virus"; "herpes labialis"; herpes labialis viruses"; "recurrences"; "recurrent herpes"; "topical administration"; "anti-infective agents"; "topical drug administration"; "corticosteroids"; "steroid"; "antiviral agents"; antiviral drugs".
Hepatitis C virus infection recurrence in the graft is common under immunosuppression, leading to an accelerated rate of graft failure.
Previous literature has shown acyclovir to be cost-effective as prophylaxis for women with genital symptomatic herpes simplex virus infection recurrence during pregnancy.
Hepatitis B immune globulins (HBIG) in combination with nucleos(t)ide analogues (NA) are effectively used for the prevention of hepatitis B virus (HBV) recurrence after liver transplantation (LT).
In a substudy of a randomized clinical trial, 308 participants were prospectively followed to investigate potential acute triggers of ocular herpes simplex virus (HSV) recurrences.
To compare the efficacy of oral antiviral prophylactic treatment for herpes simplex virus (HSV) recurrences in patients with and without self-reported atopy.
Although no infections with gonorrhea, chlamydia, or syphilis were reported during the study, all participants had anogenital HPV lesions and participants from 5 couples (6 individuals) reported anogenital herpes simplex virus (HSV) recurrences (Table 2).
To compare the incidence of herpes simplex virus (HSV) epithelial recurrence and graft survival after penetrating keratoplasty (PK) in patients with and without self-reported atopy.
This data was correlated with extracapsular spread (ECS), human papilloma virus (HPV) status, recurrence and 5-year survival.
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