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There was significant variation in the stated goal of closure decision, including limiting community spread of the virus, protecting particularly vulnerable students, and responding to staff shortages or student absenteeism.
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Sometimes infection with one closely related virus protects against another virus.
In theory, such a strategy can work because the vaccine, if given within four days of exposure to the virus, protects people from the disease.
"All the influenza viruses in humans are descendants of the 1918 virus," says Taubenberger, who published mouse experiments 8 March online in Influenza and Other Respiratory Viruses that similarly show how the 1918 virus protects against the 2009 pandemic strain.
We previously generated a type A virus possessing a chimeric HA in which the entire ectodomain of the type A HA molecule was replaced with that of the type B HA, and showed that this virus protected mice from challenge by a wild-type B virus.
The recombinant virus protected chickens from the disease following challenges with NDV and homologous and heterologous H5N1 HPAIV.
These results indicate that the attenuated vGK5 virus protects against subsequent infection and suggest that the N1L protein limits the strength of the early antiviral CD8 T cell response following respiratory infection.
Two vaccinations with this virus protected mice and guinea pigs from lethal ZEBOV challenge [ 72].
In lethal challenge experiments with chickens, an H5 HA construct protected fully and a construct expressing NP of an H5N8 virus protected partially (29, 30).
Partially purified SFV grown in WEHI-11 cells also protected mice from cancer grafts but neither highly purified SFV nor the glycoprotein from the envelope of this virus protected the mice.
Specifically, passive transfer of serum with high NAb titers from rhesus macaques vaccinated against Andes virus protected 100% of Syrian hamsters from lethal disease, even when administered 4 5 days after challenge with Andes virus (6).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com