Secondary bacterial pneumonia frequently claimed the lives of victims during the devastating 1918 influenza A virus pandemic.
Boelle, P. Y., Ansart, S., Cori, A. & Valleron, A. J.. Transmission parameters of the A/H1N1 (2009) influenza virus pandemic: a review.
This clinical trial was designed in 2008 2009 and was conducted during the A(H1N1) influenza virus pandemic in 2009 2010.
"With [our] information we show a very strong message to the field that we should not underestimate the chances of an unknown virus subtype causing the next virus pandemic," says Fouchier.
In fact, a relative the Asian tiger mosquito, Aedes albopictus, may be the culprit which has raised concerns in the world health community regarding the potential for a CHIK virus pandemic.
The 2010-11 vaccine will contain killed or weakened forms of three viruses: the swine flu virus, technically known as A/California/7/09 (H1N1 -like virus pandemic (H1N1 -like influenza; the A/Perth /16/2009 (H3N2)-like virus; and the B/Brisbane/60/2008-like virus.
Coupled with the ease of genetic manipulation, this system allows the simple and comprehensive construction of mutant protein libraries on yeast cell surface, thereby contributing to influenza virus pandemic prevention.
Indeed, the influenza virus pandemic is thought to have emerged from gene re-assortment of the North American H3N2 human-like viruses and the H1N2 swine viruses with Eurasian avian-like swine viruses (Dawood et al. 2009).
Estimates of the impact including the death toll of a possible future H5N1 virus pandemic for use in (inter)national pandemic preparedness plans do not generally exceed those of the H1N1 Spanish influenza pandemic of 1918 (3).
The substitution of a species by another species, such as Culex pipiens opens up new possibilities that might lead to new pandemic or endemic situations; in the case of Culex pipiens there is a danger of a West Nile virus pandemic (Ciota et al. 2013).
