Exact(1)
We predict that the concentration of anti-HA antibodies can be increased by optimizing the GP42-H1 vimmunizingizing dose; however, immunization with 1,000 pfu for GP42-H1 wasufficientntoto induce protection.
Similar(59)
An anti-rabies virus immunized phage-display Fab library was constructed from peripheral blood lymphocytes from vaccinated volunteers.
The virus-specific IgM ASC response was higher on day 5 than day 10 for HK03 ca virus immunized animals, but higher on day 10 than day 5 for VN04 ca virus immunized animals, indicating that the initial IgM response induced by the VN04 ca virus was slower and weaker than that induced by the HK03 ca virus.
In 1993, Okuno et al. [ 14] first reported cross-reactive antibody targeting the stalk of HA trimmer, using A/Okuda/57 (H2N2) virus to immunize mice and homologous virus for screening, and they obtained C179, an antibody which could neutralize both H1 and H2 subtypes of influenza viruses.
Premenko-Lanier et al. [ 27] once injected infant rhesus monkeys with the antisera induced by the infection with measles virus, then immunized with mixed DNA vaccines containing the hemagglutinin (HA), fusion protein (F) and nucleoprotein (NP) of measles virus.
This national policy contrasts with that of the United Kingdom, where only girls from 10 to 14 years of age who do not have detectable antibody levels to rubella virus are immunized.
Lu et al. used AcNPV a surface display expression of the hemagglutinin of H5N1 influenza virus to immunize mice.
However, immediate attention for vaccines must be directed to a coordinated international approach to vaccine evaluation, paying attention to ways in which the least amount of virus can immunize the largest number of persons.
Controlling a pandemic with vaccine and antiviral drugs will require a coordinated international approach to determine how the least amount of virus can immunize the largest segment of a population.
Towards this end, we constructed MVAΔudg-gag and MVA-gag, which commonly express a synthetic, human codon-optimized, HIV subtype-B consensus gag gene from an early viral promoter at MVA deletion site-III and differ only in their udg genotype, and used these viruses to immunize two groups of rhesus macaques (N = 6/group) with 2×108 PFU of virus at 0, 6, and 12 weeks.
The chimeric mice transduced with either c-Rel-siRNA or control viruses were immunized with KLH (100 µg) through the hind footpad.
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