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Based on this prediction, we designed 25 peptides and screened them using a HIV-luc/SARS pseudotyped virus assay.
Using a recombinant virus assay, we tried to obtain recombinant virus containing a Trp229Phe or a Trp229Tyr mutation in its RT.
The mAbs, including a whole IgG 8K8 molecule, neutralized primary HIV-1 of clades B and C in a pseudotyped virus assay with comparable, albeit relatively modest potency.
Pseudotyped viruses were produced by a recombinant virus assay.
Also for the influenza B virus assay such performance characteristics were found.
Microbicide functionality was assessed using an HIV pseudotype virus assay system representing Clade B subtypes.
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All but one of them showed high efficiency in both, reporter and virus assays.
The performance of the method was evaluated for linearity, limit of detection, precision, specificity, and agreement with commercial hepatitis C virus assays.
Drug resistance can be determined functionally by recombinant virus assays testing viral replication against every compound in vitro [8] [10].
At various times after infection mice were killed by CO2 asphyxiation and tissues harvested for virus assays or histology.
Cytoduction of the L-A and M1 killer virus into snoRNA knockout strains and subsequent killer virus assays were carried out as previously described [31].
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