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This result implies that iso-2′,3′-dideoxy sugar templates might play a role of a sugar surrogate of nucleosides for the development of anti-RNA virus agent.
This group includes enteroviruses, which attack the vertebrate intestinal tract and often invade the central nervous system as well; rhinoviruses, which infect the tissues in the vertebrate nose; and the virus agent of foot-and-mouth disease.
Respecting viruses, a team of workers has continued the study of a possible virus agent in the causation of acute rheumatism and rheumatic diseases, Dr. Salaman has continued his investigation of the antigenic structure of vaccinia virus, and Sir John Ledingham has studied the peculiar relationship that exists between the filterable viruses of rabbit myxomatosis and rabbit fibroma.
This work will be helpful for the improvement of GP-1 production on a large scale and lay a foundation for developing it to be a novel anti-plant virus agent.
For this reason, this paper was aimed at improving the yield of GP-1, which laid the foundation for developing GP-1 to be a novel anti-plant virus agent.
In the same year Friedrich Loeffler and Paul Frosch passed the first animal virus – agent of foot-and-mouth disease (aphthovirus) – through a similar filter.
Similar(52)
Nucleoside inhibitors represent an actively pursued area to develop small-molecule anti-dengue virus agents.
Several novel bicyclic furanopyrimidine deoxy nucleosides have been designed, prepared and evaluated as anti-Varicella Zoster Virus agents.
Potent antiviral effects of d-2 and l-2 indicate that nucleosides belonging to a class of D4Ns can be an excellent candidate for anti-DNA virus agents.
On the basis of selectivity index, we conceive that compound 5x may serve as a chemical probe of interest for further lead optimization studies with a general aim of developing novel and effective anti-influenza A virus agents.
None of the commonly used anti-human immunodeficiency virus agents antagonized the inhibition of HCMV by 1263W94.
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