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Legionella pneumophila, which is a causative pathogen of Legionnaires' disease, expresses its virulent traits in response to growth conditions.
When nutrients become scarce, the bacteria undergo a phenotypic switch leading to the expression of virulent traits including flagella expression and an increased resistance to antibiotics and stress.
The characteristics of such environmental pathogens include absence of any recognized animal host and maintenance of virulent traits by specific environmental associations.
In our study, all five Hie isolates contained a single copy of the cap locus, suggesting that they did not possess unusual virulent traits related to the capsule.
In this work, we studied the transcriptional profiles of two S. cerevisiae clinical strains showing virulent traits and two control non-virulent strains during a blood incubation model and detected a specific transcriptional response of clinical strains.
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The contribution of Porcine ExPECs to human ExPEC diseases could be more convincing and better explained if there is more information about the clonality, phylogenetic group, and virulent trait of commensal E. coli and human ExPECs in China.
That the EPA genes have been expanded in C. glabrata independently of the emergent pathogens is consistent with the important differences of prevalence and suggest an independent emergence of increased adherence to the human epithelium, an important virulent trait.
These findings indicate co-evolution of resistance and virulence traits favoring a more virulent genotype in a quinolone-rich clinical environment [ 80].
This has many implications for the evolution and diversity of E. faecalis, as it suggests a mechanism for the conversion of commensal E. faecalis strains to virulent ones by acquisition of the GEI-encoded virulence traits (Coburn et al., 2007).
As the epidemic grows, so does the probability that this virulent virus will acquire genetic traits for increased person-to-person transmissibility, potentially setting the stage for the next global influenza pandemic (1).
The relatedness of their genomes may explain why these clones are prone to nosocomial spread among predisposed human hosts and why virulent clades with uncommon pathogenicity traits have evolved in these clonal complexes.
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CEO of Professional Science Editing for Scientists @ prosciediting.com