Exact(19)
Statistical analysis, though, demonstrated no clear link between FlhDC dependent phenotype and virulence toward the insect.
This was also unexpected because serial passage experiments that are performed on a particular host are generally found to increase virulence toward this specific host and attenuate virulence toward others [8].
A number of other Bcc genomovars were then tested and found to display large differences in virulence toward D. melanogaster (Figure 3).
Deletion of SSN8 leads to pleiotropic phenotypes, including enhanced heterothallic a α mating and same-sex mating responses, increased production of melanin and capsule, invasive growth, modified cell wall structure and integrity, and compromised virulence toward its mammalian host.
Fortunately, the frequency of virulence toward the Rpi-blb1 R gene in the Dutch P. infestans population is still low.
Thus, recombination in the 5′-UTR of the enterovirus might have resulted in the varying virulence toward the host.
Similar(41)
Zeller et al. (2002) found that the four phylogenetic lineages of C. maydis differed in their virulence and competitiveness toward maize plants grown under greenhouse conditions.
He thinks such a swing toward virulence explains the terrible influenza pandemic of 1919, which killed more people than World War I. Normally, flu, like any other disease transmitted through the air, requires a more-or-less ambulatory host.
Findings were compared with results of standard immunoblotting and correlated with Type III secretion-dependent virulence of isolates toward cultured epithelial cells.
Adaptive mutations toward virulence can lead to founder effects that will remain detectable over the years only if gene flow with the resident population is prevented.
Additionally, in the CC30 clone, it appears that mutations in hla, agrC, and possibly crtM (squalene desaturase) are associated with the loss of virulence and evolution toward a healthcare-associated clone with epidemic potential (DeLeo et al. 2011; McAdam et al. 2012).
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