Sentence examples for virulence shift from inspiring English sources

This proposed virulence shift might contribute to the death of old or seriously ill people even in the absence of apparent disease.

A more detailed knowledge of the virulence shift mechanisms might in the future allow us to target directly the mechanisms responsible for the virulence switch.

The insertion likely occurred by recombination between the HA and nucleoprotein genes of the LPAI virus, resulting in a virulence shift.

To establish a consistent cause for a virulence shift in FCoV, specifically the predominant serotype I FCoV, we sequenced the entire genome of several FECV and FIPV specimens and then concentrated on the most conspicuous region of consistent difference by collecting and sequencing additional FECV and FIPV samples.

Studying a rapid virulence shift within a single lineage controls for many confounding factors common in studies of pathogens in natural systems (e.g., environmental conditions, host susceptibility, and pathogen ancestry) and provides an opportunity to assess the genomic changes associated with attenuation of virulence.

In the past, sequence differences in several virus genes, including those encoding membrane and spike (S) structural proteins and the so-called group-specific proteins 3c and 7b, have been implicated in the FCoV virulence shift (5 – 7, 10, 11, 19 – 22 ).

We further argue that virulence shifts across the microbiome might occur in a synchronized fashion.

Determining how quickly pathogens can exhibit shifts in virulence, and the mechanisms underlying virulence shifts, is critical for understanding and mitigating emerging infectious disease threats.

Virulence shifts of the microbiome might contribute also to this gradual nonspecific weakening at the end of life.

Not only do Bd isolates from wild populations vary in virulence, but virulence shifts can occur over short timescales when Bd is maintained in the laboratory.

The direct causes of the virulence shifts (phenotypic plasticity/facultative virulence vs. adaptive evolution/genetic changes) can be distinguished by screening for causative mutations.