Sentence examples for viral repeat from inspiring English sources

Besides such an active cleavage mechanism, the mini-F vector excision from the genomic terminal junction may also be effectuated by highly frequent homologous recombination of the viral repeat elements, supported by a different double-strand break mechanism or by a high GC content [35], [37].

Southern blots for the viral terminal repeat unit (Fig. 4a) established that latently infected fibroblasts contained on average <5 MuHV-4 genomes per cell.

Expression of ichnovirus genes were detected in parasitized larvae with 19 unique sequences identified from five PDV gene families including vankyrin, viral innexin, repeat elements, a cysteine-rich motif, and polar residue rich protein.

In our analysis, 19 unique sequences were identified from five PDV gene families including vankyrin, viral innexin, repeat elements, cysteine-rich motif, and polar residue rich protein families (Table 4).

The clonal expansion of EBV-infected T lymphocytes has been demonstrated in EBV-related HPS [ 32] and EBV-positive T cell lymphoma [ 33] on the basis of the presence of homogeneous viral terminal repeat sequences.

ORF73 is the MHV-68 episome maintenance protein and its transcription is driven by three different promoters, two of them are in the viral terminal repeats [51].

For the serial in vivo MR spectroscopy data and viral loads, repeated measures analysis of variance RM-ANOVAA) in combination with Holm's t-tests was employed to isolate differences between time-points within the cohorts using JMP 7.0 (SAS, Cary, NC).

In fact, the steady-state level of ihprolC-PP197 mRNA was 5 to 10 times lower than that of a transgene rolC-PP2x1977) cofposed of the same regulatory and transcribed regions of the ihprolC-PP197 construct, but bearing the 197 bp viral sequences repeated in a direct orientation (Fig. 3, panel B, lanes 2 4).

Interestingly, the expression levels of 2 genes from the NF-κB pathway were also altered; TRAF family member-associated NFκB activator (TANK) was increased 50-fold, whereas the expression of the anti-apoptotic baculo-viral IAP repeat-containing-2 gene (BIRC2) diminished approximately 10-fold (P = 0.04).

Although the enzyme was active on DNA substrates devoid of viral long terminal repeat (LTR) sequences, the presence of LTR regions stimulated significantly this activity.

A recent clinical trial for X-CGD using a spleen focus-forming virus (SFFV based γ-retroviral vector has demonstrated clear therapeutic benefits in several patients although complicated by enhancer-mediated mutagenesis and diminution of effectiveness over time due to silencing of the viral long terminal repeat (LTR).