Exact(2)
There is a need to understand the mechanism of immune activation and how it gets repressed by viral overload so the major elements of immune system that plays an important role are discussed below in detail.
In the absence of NF-κB activity, p50 −/− and p65 −/− cells were able to undergo rapid apoptosis upon EMCV infection prior to viral replication, thus pre-emptively preventing progeny viral overload and spread (Schwarz et al, 1998).
Similar(6)
ER stress is induced by accumulation of unfolded proteins (unfolded protein response, UPR) or by excessive protein demand caused by viral infection (ER overload response, EOR) [ 19, 21].
Although we ruled out other potential and common causes of raised liver enzyme levels, such as viral hepatitis, iron overload, and high alcohol consumption, we are aware that this definition has a limited sensitivity and specificity, 36 and thus our results for non-alcoholic steatohepatitis should be interpreted with caution.
In alcoholic and viral liver injury iron overload accompany severe necroinflammatory process [ 30].
Acquired fibrosis may result from the action of a number of pathogenic factors and toxic exposures such as long-term excessive alcohol consumption, cholestasis, autoimmune liver diseases, iron or copper overload, chronic viral hepatitis or the presence of non-alcoholic fatty liver disease (NAFLD).
The site's early viral activity almost immediately overloaded the servers, leading to more than a few hours of downtime.
It may be a general phenomenon during virus infection that the amount of signal sequence-containing viral polypeptides present simultaneously overloads the translocation apparatus.
Related(1)
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