Sentence examples for viral administration from inspiring English sources

Evidence further suggests that locoregional viral administration may improve viral efficacy while minimizing toxicity.

Consequently, the DTSTA approach is a hybrid method of transcriptional and genomic augmentation that can provide higher level reporter gene expression potentially with a lower dose of viral administration.

None of the NV1023-treated animalsuffereded from clinically apparent side effects attributable to viral administration.

GPI-EGFP was chased to the plasma membrane of 293 cells by a 4 h treatment with cycloheximide before viral administration.

For all experiments, tumors were grown up to 200-400 mm3 in size (4-6 weeks) before viral administration.

Importantly, in vivo luciferase bioluminescence measured 6 days after viral administration significantly correlated with CRAd antitumor effect at day 36.

As demonstrated above (Fig. 1A), viral antigen administration by IV route results in a diminished number of antigen-specific tet+ CD8+ T cells at days 7 and 14 p.i. compared to SubQ virus inoculation where there is a substantial accumulation of antigen-specific tet+ CD8+ T cells in the liver.

Sasano et al. reported an increase of up to 80% in cardiac transduction efficiencies in a porcine model by using a combination of VEGF, adenosine, calcium, and nitroglycerin (NTG) infusion prior to the viral vector administration.

In fact, normalization of DYRK1A or SNX27 expression in the hippocampi of adult Ts65Dn mice by strategies based on viral vector administration has shown rescue of synaptic deficits and partial recovery of behavioural abnormalities [ 37, 38].

These results are very promising in that the LV platform could be tailored towards an effective treatment option for CVD that require long-term expression of the therapeutic gene, without the adverse effects of adenoviral vectors obviating the need for repeated viral vector administration.

Induction of adaptive immune responses to virus exposures during anti-viral drug administration, i.e., a "chemo-vaccination" effect, could contribute to PrEP efficacy.