According to the dominant model, ADHD is viewed as an executive dysfunction [ 2, 3], but alternative accounts present ADHD as a motivational dysfunction [ 4], arising from altered processes within fronto-striatal circuits [ 5, 6].
Moreover, albuminuria has been viewed as a mirror of microvascular dysfunction, which results in vascular leaking of not only albumin, collagen and cholesterol, but also advanced glycation end products, and is the primary mediator of myocardial fibrosis due to the suppression of collagen turnover via impaired crosslinking of collagen [ 29, 36].
Although bipolar disorder historically has been viewed as a disease involving only episodic dysfunction, increasing evidence indicates that this is not the case for a substantial proportion of patients.
Our results support a recent metabolomics study showing that patients with DN have reduced mitochondrial metabolites in urine (Sharma et al., 2013) and we propose that DN could be viewed as a disease of acquired mitochondrial dysfunction.
What was once viewed as a bourgeoning dynasty offered inconsistency and dysfunction this season.
Sepsis-associated liver dysfunction is traditionally viewed as a late feature of critical illness indicated by jaundice and hyperbilirubinemia.
Adipose tissue dysfunction can be viewed as a combination of pro-inflammatory changes in adipose tissue and changes in the endocrine function of adipose tissue as witnessed by changes in plasma cytokine and especially plasma adipokine levels.
Even sexual dysfunction, which for years was viewed as a small price to pay for survival, is now treated like any other side effect.
Turnbull is viewed as a possible antidote to the never-ending spectacle of gaffes, unpopular policies, and dysfunction that have plagued Australian politics and made international headlines under Abbott's tenure.
