Exact(7)
Fraser, A. G. & Marcotte, E. M. A probabilistic view of gene function.
The enzyme view of gene function, as envisaged by Kühn and by Beadle and Tatum, though with cautious reservation, gave the idea of genetic specificity a new twist and helped to pave the way to the molecularization of the gene to which this section will be devoted (see also Kay 1993).
Our strategy emphasizes that a gene should be defined as an element in the network of its interactions, in agreement with the post-genomic view of gene function [40].
The MSGR has a limited view of gene function because it uses gene expression data exclusively.
Such an extended view of gene function is essential for the prediction of plant responses to changing climates.
Studying protein complexes therefore provides an aggregative or "systems level" view of gene function and regulation than studying individual proteins (genes).
Similar(53)
Much of our knowledge on the functions of genes, both in health and disease, is derived from molecular biological experiments with specific model systems, which often provide a biased and context-specific view of gene functions.
While annotation from these resources can be accessed through web-based homology searches, for many laboratory collections of ESTs it is difficult to use existing tools to achieve a systems-level view of gene functions and relationships.
Discrepancies in symbol usage between rat genome databases may reflect contradictory views of gene function, and so the R2 status is used to draw attention to such possibilities.
Such a view about the essentiality of gene function, differs from a synthetic biology view, which considers the genes necessary to specify an operable system which functions outside the natural world.
The WEGO software was then used to perform GO functional classification of all sequences to view the distribution of gene functions of the species at the macro level [ 37].
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